Apigenin is a flavonoid found in chamomile tea, parsley, and celery, and is considered the primary compound responsible for chamomile's traditional calming effects. It binds to benzodiazepine sites within the GABA-A receptor complex, producing a mild, modulatory (rather than forceful) calming effect.
Clinical Summary
Research indicates Apigenin reduces locomotor activity and supports the transition into deeper, restorative Slow-Wave Sleep stages without disrupting the natural sleep cycle.
Dosage Guidelines
50mg, typically taken 30 to 60 minutes before desired sleep time.
Safety & Side Effects
Considered very safe; no significant adverse effects commonly reported at supplemental doses.
Known Interactions
May have a mild additive sedative effect when combined with other calming compounds (e.g. Magnesium, L-Theanine) or CNS depressants such as alcohol or benzodiazepines.
Medical Disclaimer
The information provided in this clinical review is for educational and informational purposes only. It is not intended to be a substitute for professional medical advice, diagnosis, or treatment.
*These statements have not been evaluated by the Food and Drug Administration (FDA). This product or ingredient is not intended to diagnose, treat, cure, or prevent any disease.
Always consult your physician or other qualified health provider with any questions you may have regarding a medical condition, or before beginning any new diet, fitness, supplement, or treatment regimen, especially if you have pre-existing medical conditions or are taking prescribed medications.
