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HFL Health Findings Lab

Coleus

Fat burning aid. A botanical extract that stimulates cAMP production, often used for metabolic support.

Evidence-Based
Fact-Checked
Updated: Aug 20, 2026
Clinical Profile

Coleus (Coleus Forskohlii) contains the active compound forskolin, which directly activates the enzyme adenylate cyclase, raising intracellular levels of cyclic AMP (cAMP). This regulates crucial metabolic processes.

Clinical Summary

Research indicates forskolin may help improve body composition and stimulate fat release, though studies on direct blood sugar control are mixed.

Dosage Guidelines

250mg to 500mg of a 10% standardized extract daily, usually divided into two doses.

Safety & Side Effects

May cause mild gastrointestinal distress or lower blood pressure in sensitive individuals.

Known Interactions

May interact with blood thinners and anti-hypertensive medications.

Scientific References

Medical Disclaimer

The information provided in this clinical review is for educational and informational purposes only. It is not intended to be a substitute for professional medical advice, diagnosis, or treatment.

*These statements have not been evaluated by the Food and Drug Administration (FDA). This product or ingredient is not intended to diagnose, treat, cure, or prevent any disease.

Always consult your physician or other qualified health provider with any questions you may have regarding a medical condition, or before beginning any new diet, fitness, supplement, or treatment regimen, especially if you have pre-existing medical conditions or are taking prescribed medications.

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