Leucine is one of the three branched-chain amino acids (BCAAs) and is considered the key signaling amino acid for initiating muscle protein synthesis via activation of the mTOR pathway.
Clinical Summary
Extensively studied for its central role in triggering post-exercise muscle protein synthesis; considered the most anabolically potent of the essential amino acids.
Dosage Guidelines
Approximately 2g to 3g per dose is generally considered sufficient to maximally stimulate muscle protein synthesis.
Safety & Side Effects
Very well tolerated at recommended doses; excessive long-term intake in isolation may create an amino acid imbalance.
Known Interactions
No major known drug interactions at supplemental doses.
Medical Disclaimer
The information provided in this clinical review is for educational and informational purposes only. It is not intended to be a substitute for professional medical advice, diagnosis, or treatment.
*These statements have not been evaluated by the Food and Drug Administration (FDA). This product or ingredient is not intended to diagnose, treat, cure, or prevent any disease.
Always consult your physician or other qualified health provider with any questions you may have regarding a medical condition, or before beginning any new diet, fitness, supplement, or treatment regimen, especially if you have pre-existing medical conditions or are taking prescribed medications.
