Manganese is a cofactor for several enzymes, including manganese superoxide dismutase (an important antioxidant enzyme) and enzymes involved in bone formation and carbohydrate metabolism.
Clinical Summary
Essential trace mineral with well-documented roles in bone health and antioxidant defense; deficiency is rare in developed countries but relevant in restrictive diets.
Dosage Guidelines
1.8mg to 2.3mg daily is the standard adequate intake for adults.
Safety & Side Effects
Very safe at nutritional doses; chronic excessive intake (well above supplemental levels) has been linked to neurological effects.
Known Interactions
May interact with certain antibiotics (tetracyclines, fluoroquinolones), reducing their absorption; take at separate times.
Medical Disclaimer
The information provided in this clinical review is for educational and informational purposes only. It is not intended to be a substitute for professional medical advice, diagnosis, or treatment.
*These statements have not been evaluated by the Food and Drug Administration (FDA). This product or ingredient is not intended to diagnose, treat, cure, or prevent any disease.
Always consult your physician or other qualified health provider with any questions you may have regarding a medical condition, or before beginning any new diet, fitness, supplement, or treatment regimen, especially if you have pre-existing medical conditions or are taking prescribed medications.
