Uva Ursi (Arctostaphylos uva-ursi), also known as bearberry, is a low-growing evergreen shrub. Its primary active compound, arbutin, converts to hydroquinone in the urinary tract, where it exerts a strong antiseptic and mild diuretic effect. It is a common ingredient in detox, bloating, and UTI-support formulas.
Clinical Summary
Clinically shown to effectively inhibit bacteria that cause UTIs (like E. coli). However, it is intended for acute, short-term use (no longer than 7-14 days) rather than daily maintenance.
Dosage Guidelines
400-800mg of arbutin equivalent daily, divided into 2-3 doses. Requires an alkaline urine environment to work effectively.
Safety & Side Effects
Nausea, vomiting, or a green-brown discoloration of urine. High doses over long periods can cause liver or kidney toxicity due to hydroquinone accumulation.
Known Interactions
Do not take with substances that make urine acidic (like high doses of Vitamin C or cranberry juice), as this nullifies its antiseptic effect.
Medical Disclaimer
The information provided in this clinical review is for educational and informational purposes only. It is not intended to be a substitute for professional medical advice, diagnosis, or treatment.
*These statements have not been evaluated by the Food and Drug Administration (FDA). This product or ingredient is not intended to diagnose, treat, cure, or prevent any disease.
Always consult your physician or other qualified health provider with any questions you may have regarding a medical condition, or before beginning any new diet, fitness, supplement, or treatment regimen, especially if you have pre-existing medical conditions or are taking prescribed medications.