Independent reviews · Updated weekly Editorial & affiliate disclosures
HFL Health Findings Lab

Vitamin K2

A fat-soluble vitamin that works alongside Vitamin D3 to direct calcium toward bones and away from soft tissue.

Clinical Profile

Vitamin K2 (menaquinone) activates proteins (such as osteocalcin and matrix Gla-protein) that regulate calcium deposition, directing it toward bone mineralization and away from arterial walls and soft tissue.

Clinical Summary

Frequently paired with Vitamin D3 in supplement formulations because the two nutrients work synergistically in calcium metabolism; research supports this pairing for supporting healthy bone density and cardiovascular calcium balance.

Dosage Guidelines

90mcg to 180mcg of MK-7 daily.

Safety & Side Effects

Very well tolerated; no significant adverse effects commonly reported at supplemental doses.

Known Interactions

Can reduce the effectiveness of blood-thinning medications such as Warfarin, which work via Vitamin K antagonism; consult a physician before combining.

Medical Disclaimer

The information provided in this clinical review is for educational and informational purposes only. It is not intended to be a substitute for professional medical advice, diagnosis, or treatment.

*These statements have not been evaluated by the Food and Drug Administration (FDA). This product or ingredient is not intended to diagnose, treat, cure, or prevent any disease.

Always consult your physician or other qualified health provider with any questions you may have regarding a medical condition, or before beginning any new diet, fitness, supplement, or treatment regimen, especially if you have pre-existing medical conditions or are taking prescribed medications.

Articles discussing Vitamin K2

Get new reviews in your inbox — weekly, never spammy.

Join our community of readers who use Health Findings Lab to cut through supplement marketing noise.