Quick Reference
- Scientific Rating
-
4.7/ 5.0
- Primary Mechanism
- Dopaminergic action inhibiting prolactin secretion to support luteal phase progesterone synthesis
- Standardized Form
- Fruit extract (standardized to agnusides or casticin)
Vitex agnus-castus, commonly known as chasteberry, is highly effective for female hormonal balance. It operates primarily at the level of the pituitary gland. By binding to dopamine D2 receptors, it inhibits the excess secretion of prolactin. This mild reduction in prolactin helps normalize the luteal phase of the menstrual cycle, naturally supporting the body's own production of progesterone.
Table of Contents
Clinical Summary
Strong clinical consensus supports its use for relieving physical and psychological symptoms of PMS, particularly breast tenderness, mood swings, and fluid retention.
Dosage Guidelines
20mg to 40mg daily of standardized extract, ideally taken in the morning.
Safety & Side Effects
Exceptionally safe. Occasional mild nausea, headache, or temporary menstrual changes during the first month of use.
Known Interactions
Avoid concurrent use with dopamine agonists (e.g., Parkinson's medications) or oral contraceptives.
Scientific References
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Medical Disclaimer
The information provided in this clinical review is for educational and informational purposes only. It is not intended to be a substitute for professional medical advice, diagnosis, or treatment.
*These statements have not been evaluated by the Food and Drug Administration (FDA). This product or ingredient is not intended to diagnose, treat, cure, or prevent any disease.
Always consult your physician or other qualified health provider with any questions you may have regarding a medical condition, or before beginning any new diet, fitness, supplement, or treatment regimen, especially if you have pre-existing medical conditions or are taking prescribed medications.
